Cocker Spaniel – Disease Predisposition

English Cocker Spaniel

COCKER SPANIEL

  • Patent ductus arteriosus
  • Dilated cardiomyopathy (DCM) (American Cocker Spaniels)
  • Familial cardiomyopathy (English Cocker Spaniels)
  • Sick sinus syndrome
  • Dermatological conditions
  • Atopy
  • Primary seborrhea (American Cocker Spaniels)
  • Congenital hypotrichosis (American Cocker Spaniels)
  • Black hair follicular dysplasia (American Cocker Spaniels)
  • Food hypersensitivity
  • Vitamin-A-responsive dermatosis
  • Tail-dock neuroma
  • Intertrigo
  • Onychodystrophy
  • Anal sac disease
  • Hypothyroidism
  • Brachyury
  • Chondrodysplasia
  • Congenital elbow luxation
  • Foramen magnum dysplasia
  • Incomplete ossification of the humeral condyle
  • Inguinal/scrotal herniation Females predisposed
  • Temporomandibular dysplasia
  • Cranial cruciate ligament rupture (American Cocker Spaniels)
  • Spondylosis deformans (American Cocker Spaniels)
  • Patellar luxation (American Cocker Spaniels)
  • Umbilical hernia (American Cocker Spaniels)
  • Prognathia (American Cocker Spaniels)
  • Gastrointestinal diseases
  • Cricopharyngeal achalasia
  • Oropharyngeal neoplasia
  • Chronic hepatitis
  • Alpha-1-antitrypsin-related hepatitis
  • Immune-mediated haemolytic anaemia
  • Platelet storage-pool deficiency (American Cocker Spaniels)
  • Haemophilia B (American Cocker Spaniels)
  • Factor X deficiency
  • Immune-mediated thrombocytopaenia
  • Immune-mediated cardiomyopathy
  • Basal cell tumour
  • Sweat gland tumour
  • Trichoepithelioma
  • Cutaneous papillomas
  • Sebaceous gland tumours
  • Cutaneous plasmacytoma
  • Canine cutaneous histiocytoma
  • Trichoblastoma
  • Fibrosarcoma
  • Non-epitheliotropic lymphoma
  • Perianal (hepatoid) gland adenomas
  • Anal sac adenocarcinoma (English Cocker Spaniels)
  • Melanoma
  • Lipoma
  • Limbal melanoma
  • Congenital deafness
  • Congenital vestibular disease (English Cocker Spaniels)
  • Acquired vestibular disease secondary to otitis interna
  • Intervertebral disc disease
  • True epilepsy
  • Lysosomal storage disease – ceroid lipofuscinosis
  • Idiopathic facial paralysis
  • Multisystem neuronal degeneration
  • Entropion (usually upper lateral eyelids) (American and English Cocker Spaniels)
  • Ectropion (usually lower eyelids) (American and English Cocker Spaniels)
  • Distichiasis (American and English Cocker Spaniels) – High incidence (>80% in some surveys)
  • Trichiasis (English Cocker Spaniels)
  • Lacrimal punctal aplasia (usually lower duct) (American and English Cocker Spaniels)
  • Limbal melanoma (American and English Cocker Spaniels)
  • Refractory corneal ulceration (American Cocker Spaniels)
  • Keratoconjunctivitis sicca (American Cocker Spaniels)
  • Corneal dystrophy (American Cocker Spaniels)
  • Lipid dystrophy
  • Corneal (endothelial) dystrophy (American Cocker Spaniels)
  • Glaucoma
  • Primary glaucoma/goniodysgenesis (English Cocker Spaniels)
  • Primary glaucoma (American Cocker Spaniels)
  • Lens luxation (English Cocker Spaniels)
  • Persistent pupillary membranes (English Cocker Spaniels)
  • Cataract (English Cocker Spaniels)
  • Cataract (American Cocker Spaniels)
  • Multifocal retinal dysplasia (American Cocker Spaniels)
  • Generalised progressive retinal atrophy (English Cocker Spaniels)
  • Generalised progressive retinal atrophy (GPRA) (American Cocker Spaniels)
  • Central progressive retinal atrophy (CPRA) or retinal pigment epithelial dystrophy (RPED) (English Cocker Spaniels)
  • Optic nerve coloboma (American Cocker Spaniels)
  • Multiple ocular defects (English Cocker Spaniels) – Mode of inheritance unknown – Defects may include microphthalmia, persistent pupillary membranes and congenital cataract
  • Neuronal ceroid lipofuscinosis
  • Familial renal disease (English Cocker Spaniels)
  • Struvite (magnesium ammonium phosphate) urolithiasis
  • Calcium phosphate urolithiasis (hydroxyapatite and carbonate apatite)
  • XX sex reversal
  • Penile hypoplasia
  • Spontaneous thymic haemorrhage
  • Bronchiectasis (American Cocker Spaniels)

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