Hemophilia a Brief Description
Hemophilia is a bleeding condition of varying seriousness which is a result of an insufficiency in particular clotting factors. Usually the body reacts to damage which induces blood loss by using a complex defence mechanism. This comprises local alterations in the injured blood vessels, activation of blood cells named platelets, and also the coagulation (clotting) process. The majority of inherited bleeding conditions are the consequence of defective platelet function or an insufficiency in a number of of the components active in the blood clotting system.
Hemophilia is considered the most widespread inherited coagulation factor deficiency. Hemophilia A is caused by a deficiency in factor VIII, and hemophilia B in factor IX. Hemophilia A is much more prevalent than hemophilia B, and can vary in severity according to the degree of factor VIII activity. Hemophilia B is frequently a serious bleeding disorder.