Home Disease Predispositions
Posted By: Paul
BEAGLE
Pulmonic stenosis
Coronary artery vasculitis – reported as affecting 34% of young Beagles
Canine juvenile polyarteritis syndrome
Congenital hypotrichosis
Black hair follicular dysplasia
Ehler-Danlos syndrome Also known as cutaneous asthenia
Familial vasculopathy
Canine truncal solar dermatitis
Zinc-responsive dermatosis
Lymphocytic thyroiditis (causing hypothyroidism)
Thyroid neoplasia (may be associated with hyper- or hypothyroidism, but most are euthyroid)
Hyperadrenocorticism: pituitary-dependent (PDH)
Diabetes mellitus
Chronic hepatitis
Severe combined immunodeficiency
Selective IgA deficiency – Leads to chronic respiratory conditions and dermatitis
Pyruvate kinase deficiency
Non-spherocytic haemolytic anaemia
Factor VII deficiency
Primary idiopathic hyperlipidaemia
Polyarthritis/meningitis
Multiple epiphyseal dysplasia
Brachyury
Mast cell tumours
Actinic keratosis (solar keratosis)
Sebaceous gland tumours
Haemangiopericytoma
Perianal (hepatoid) gland adenomas
Cutaneous haemangioma
Thyroid neoplasia
Pituitary tumour resulting in hyperadrenocorticism
Lymphosarcoma (malignant lymphoma)
Congenital vestibular disease
Congenital deafness
Intervertebral disc disease Relatively common condition
Lysosomal storage disease – GM1 gangliosidosis
Lysosomal storage disease – neuronal glycoproteinosis (Lafora’s disease)
Cerebellar degeneration – reported in Japan
True epilepsy
Narcolepsy-cataplexy
Lissencephaly – a rare disease reported in this breed
Hound ataxia Reported in the UK
Meningitis and polyarteritis
Spina bifida
Prolapse of the gland of the nictitating membrane (‘cherry eye’)
Corneal dystrophy
Stromal lipid dystrophy – Reports suggest it affects approximately 17% of Beagles aged 8–15 years
Glaucoma
Lens luxation
Cataract
Multifocal retinal dysplasia
Tapetal degeneration
Generalised progressive retinal atrophy (GPRA)
Micropapilla
Optic nerve hypoplasia
Congenital cataract with microphthalmia
Microphthalmia-microphakia-persistent pupillary membrane (PPM) syndrome
Multiple ocular defects of the posterior segment – Defects include retention of the hyaloid system, excessive myelination of the optic disc and neovascularisation of the retina, with a tendency for intraocular haemorrhage
Hypochondroplasia – Accepted as breed standard
Renal (glomerular) amyloidosis
Unilateral renal agenesis – High prevalence reported in some families of Beagles
XX sex reversal
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