Poodle – Disease Predisposition

Poodle

POODLE

Cardiovascular conditions

Patent ductus arteriosus

• Common congenital abnormality

Endocardiosis
  • Also known as chronic valvular disease
Dilated cardiomyopathy
  • Standard Poodles over-represented in one study

Dermatological conditions

Malassezia dermatitis
Rabies-vaccine-associated vasculitis and alopecia
Seaonal flank alopecia
  • Miniature Poodles predisposed
Congenital hypotrichosis (Toy and Miniature Poodles)
Colour-dilution alopecia
  • Standard Poodles predisposed
Post-injectional calcinosis circumscripta
Primary lymphoedema
Melanotrichia
Nasal depigmentation
  • Also known as Dudley nose
Anal sac disease (Toy and Miniature Poodles)
Zinc-responsive dermatosis (Standard Poodles)
Granulomatous sebaceous adenitis
Idiopathic chronic ulcerative blepharitis
Idiopathic sterile nodular panniculitis

• Females predisposed

Drug reactions

Glucocorticoids

Endocrine conditions

Adult-onset growth-hormone-responsive dermatosis (Toy and Miniature Poodles)
  • Breed predisposition
Hypothyroidism
  • Breed reported in some texts to be at increased risk
Hypoadrenocorticism (Standard Poodles)
Hyperadrenocorticism: pituitary-dependent (PDH) and adrenocortical tumour (AT)
  • Possible breed predisposition (PDH and AT)
Diabetes mellitus
  • Possible breed predisposition
Insulinoma (Standard Poodles)
  • Higher incidence seen in this breed
Primary hypoparathyroidism (Miniature Poodles)
  • Uncommon condition
  • Breed at increased risk in some surveys

Gastrointestinal conditions

Salivary mucocoele
  • Possible breed predisposition
Cricopharyngeal achalasia
  • Possible breed predisposition
Gastric dilatation-volvulus (Standard Poodles)
  • Possible breed predisposition
Haemorrhagic gastroenteritis (Toy and Miniature Poodles)
  • Breed predisposition
Lobular dissecting hepatitis (Standard Poodles)
  • Possible breed predisposition
Cholelithiasis
  • Possible breed predisposition

Haematological/immunological conditions

Non-spherocytic haemolytic anaemia (Miniature Poodles)
  • Rare
Immune-mediated haemolytic anaemia
  • Common disease
Immune-mediated thrombocytopaenia (Miniature and Toy Poodles)
  • Common
  • Inheritance likely
Von Willebrand’s disease
Systemic lupus erythematosus

Musculoskeletal conditions

Inguinal/scrotal herniation
Perineal hernia
Medial patellar luxation
  • Significant hereditary component suspected (Miniature and Toy Poodles)
Aseptic necrosis of the femoral head (Miniature and Toy Poodles)
  • Also known as Legg-Calve-Perthe’s disease
Miniature Poodle multiple enchondromatosis
Miniature Poodle multiple epiphyseal dysplasia
  • Rare
Miniature Poodle pseudoachondroplasia
Shoulder luxation (Miniature Poodles)
  • Congenital
Congenital scapulohumeral luxation
  • Rare condition
Delayed/non-union of fractures of the distal third of the radius and ulna in miniature and toy breeds (Toy and Miniature Poodles)

Neoplastic conditions

Basal cell tumour (Miniature Poodles)
  • Reported to be at increased risk
Trichoepithelioma (Standard Poodles)
  • Possible breed predisposition
Pilomatrixoma (Miniature and Standard Poodles)
  • Possible breed predisposition
Sebaceous gland tumours
  • Possible breed predisposition to nodular sebaceous hyperplasia
Squamous cell carcinoma of the digit (Standard Poodles)
  • Possible breed predisposition
Insulinoma (Standard Poodle)
Pituitary tumour resulting in hyperadrenocorticism
Adrenocortical tumour resulting in hyperadrenocorticism
Lymphosarcoma (malignant lymphoma)
  • Higher incidence noted in this breed
Limbal melanoma
  • Possible breed predisposition
Oral melanoma
  • Possible breed predisposition
Testicular neoplasia (Miniature and Standard Poodles)
  • Believed to be a breed at increased risk

Neurological conditions

Acquired vestibular disease secondary to otitis interna
  • Breed predisposition to chronic otitis externa which may progress to otitis media/interna
Congenital deafness (Miniature Poodles)
Intervertebral disc disease
  • Breed predisposition
  • Relatively common condition
Lysosomal storage disease – globoid cell leukodystrophy (Krabbe’s disease)
  • Inheritance suspected
Lysosomal storage disease – neuronal  glycoproteinosis (Lafora’s disease)
  • Inheritance suspected
Lysosomal storage disease – sphingomyelinosis (Niemann-Pick disease) (Miniature and Toy Poodles)
  • Inheritance suspected
Cerebellar degeneration (Miniature Poodles)
True epilepsy (Miniature and Standard Poodles)
  • Inheritance suspected
Hydrocephalus (Toy Poodles)
  • Congenital
Narcolepsy-cataplexy (Miniature and Standard Poodles)
  • Inheritance suspected
Hypoglycaemia (as a possible cause of seizures in Miniature and Toy Poodles)
  • Breed predisposition
Demyelinating myelopathy (Miniature Poodles)
  • Inheritance suspected
Atlantoaxial subluxation (Miniature and Toy Poodles)
  • Congenital
  • Relatively common in these breeds
Granulomatous meningoencephalitis (GME)(Miniature and Toy Poodles)
  • Breed predisposition

Ocular conditions

Entropion (usually medial lower lids)

Breed predisposition

Distichiasis (Toy and Miniature Poodles)
  • Breed predisposition
Caruncular trichiasis
  • Breed predisposition
Lacrimal punctal aplasia (Toy and Miniature Poodles)
  • Congenital condition
Medial canthal pocket syndrome (Standard Poodles)
  • Breed predisposition; resulting from head shape
Pigmentary keratitis (Miniature Poodles)
  • Breed predisposition
Microcornea
  • Congenital
Refractory corneal ulceration (Miniature and Toy Poodles)
  • Breed predisposition
Congenital, sub-epithelial, geographic corneal dystrophy
  • Congenital condition; predisposed breed
Limbal melanoma
  • Possible breed predisposition
Glaucoma (Miniature and Toy Poodles)
  • Breed predisposition
Degeneration of the vitreous body (Miniature Poodles)
Lens luxation (Toy Poodles)
  • Breed predisposition
Cataract (Standard Poodles)
Cataract (Toy and Miniature Poodles)
  • Inheritance suspected
Generalised progressive retinal atrophy (GPRA) (Toy and Miniature Poodles)
Micropapilla (Miniature and Toy Poodles)
  • Congenital condition
Optic nerve hypoplasia (Miniature and Toy Poodles)
  • Congenital condition; inheritance suspected
Pseudopapilloedema (Miniature Poodles)
Multiple ocular defects (Standard Poodles)
  • Inheritance suspected

Physiological conditions

Red blood cell macrocytosis

Renal and urinary conditions

Familial renal disease (renal dysplasia) (Standard Poodle)
Ectopic ureters (Toy and Miniature Poodles)
  • Congenital anomaly, higher incidence reported in this breed
Calcium oxalate urolithiasis (Miniature Poodles)
  • Higher incidence has been noted in this breed in some surveys
Struvite (magnesium ammonium phosphate) urolithiasis (Miniature Poodles)
  • Higher incidence has been noted in this breed in some surveys
Calcium phosphate urolithiasis(hydroxyapatite and carbonate apatite) (Miniature Poodles)
  • Higher incidence has been noted in this breed in some surveys
Calcium phosphate urolithiasis (brushite) (Miniature Poodles)
  • Higher incidence has been noted in this breed in some surveys

Reproductive conditions

Male pseudohermaphroditism
  • Congenital abnormality reported in this breed
Cryptorchidism (Toy and Miniature Poodles)
  • Believed to be a breed at increased risk
Testicular neoplasia (Miniature and Standard Poodles)
  • Believed to be a breed at increased risk

Respiratory conditions

Tracheal collapse (Miniature and Toy Poodles)

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