Mastiff – Disease Predisposition

Mastiff

MASTIFF

Cardiovascular conditions

Pulmonic stenosis
Mitral dysplasia
  • Congenital
  • Genetic basis suspected

Gastrointestinal conditions

Gastric dilatation-volvulus
  • Possible breed predisposition

Musculoskeletal conditions

Hip dysplasia
  • This breed has the eighteenth worst breed mean score in the BVA – KC Hip Dysplasia Scheme as of October 2001
Cranial cruciate ligament rupture
  • Young animals may be predisposed in this breed

Ocular conditions

Entropion (may be associated with macropalpebral fissure)
  • Breed predisposition; polygenic inheritance likely
Ectropion (may be associated with macropalpebral fissure)
  • Breed predisposition; polygenic inheritance likely
Macropalpebral fissure resulting in combined entropion-ectropion (‘diamond eye’)
  • Breed predisposition; genetic basis incompletely understood
Eversion of the cartilage of the nictitating membrane
  • Breed predisposition; inheritance suspected
Prolapse of the gland of the nictitating membrane (‘cherry eye’)
  • Breed predisposition
Corneal dystrophy
  • Breed predisposition; not known if inherited
Persistent pupillary membranes and microphthalmia

• Recessive inheritance has been suggested

Cataract
  • Inheritance suspected

Renal and urinary conditions

Cystine urolithiasis
  • Higher incidence reported in this breed in some American surveys

Reproductive conditions

Vaginal hyperplasia
  • Breed predisposition

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